Antone’s Famous Po’ Boys Plans New Houston Medical Center Location

For the first time since opening the Galleria location back in the early 2000s, Legacy Restaurants is opening a new, full-fledged Antone’s Famous Po’ Boys at 6618 Fannin in the Medical Center. Specifically, it will be on the ground level of Medical Towers Building at 1709 Dryden (across from the Dryden/TMC METRORail stop and Texas Children’s Hospital) and is expected to debut late this summer.

“We have been anxious to find the right spot for an Antone’s in the Medical Center, and this location is fantastic,” said Legacy Restaurants CEO Jonathan Horowitz via press release.

Local builder Construction Concepts is developing the space. The design includes seating for 50, counter service and “an updated interior design” that includes a blue and white color scheme and tile accents, with tiles even inlaid into the tables. The two existing Antone’s Famous Po’ Boys restaurants at 4520 San Felipe and 2724 West TC Jester are going to benefit from that new design as well, as there are plans to give both spaces the same sort of updates.

The Piggy at Antone's
The Piggy with ham salad and pickles at Antone’s Famous Po’ Boys. Photo courtesy of Legacy Restaurants

Antone’s Famous Po’ Boys at the Medical Center is going to also break new ground with its mealtimes. It’s the first location ever to serve breakfast in addition to lunch and dinner. As is the case with the other two locations, it is also going to function as a pick-up spot for catering orders. (Delivery to the Medical Center and surrounding areas is also an option.)

While Antone’s is of course known for its namesake items, the po’ boys (specifically the Original, Super Original, Piggy, Turkey & Swiss and Tuna) the menu is actually fairly extensive. It includes soups (such as a variety of gumbos), hearty hot dishes like red beans and rice, warm muffulettas, fried seafood plates and much more. There are also limited-time seasonal specials, salads and various sides as well as freshly baked brownies and cookies.

Tray of fried seafood with French fries
The fried seafood platter at Antone’s Famous Po’Boys. Photo by Becca Wright

With this latest development, Horowitz says: “We see this as the first step in continued growth for Antone’s, with new restaurants as well as the expansion of our sandwich and condiment distribution business.”

Really, though, it’s the latest in a series. In July 2016, the company opened a grab-and-go kiosk at 3 Greenway Plaza, home to the city’s best office building food court.

In October 2018, the company increased production in order to start shipping po’ boys overnight to Austin. Before that effort even started, according to a company press release it was already sending “30,000-35,000 sandwiches each week to more than 200 H-E-B, Kroger and Randalls stores in Southeast Texas and western Louisiana”.

At this rate of growth, there’s probably an Antone’s po’ boy coming soon to a refrigerator near you — if it’s not already there.

Disclosure: Antone’s Famous Po’ Boys is a current Houston Food Finder sponsor.

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